News
Men's Health & TestosteroneThe Journal of Clinical Endocrinology & Metabolism

Landmark Study Confirms Testosterone Drops 1-2% Per Year After 30

March 15, 2023

The Baltimore Longitudinal Study of Aging found that testosterone declines at a consistent rate with age, with hypogonadal levels reaching 20% of men over 60 and 50% over 80.

Read the original article at The Journal of Clinical Endocrinology & Metabolism

Kairos™'s Take

Kairos™'s perspective on this story

The Baltimore Longitudinal Study of Aging remains one of the most important pieces of evidence we have about what happens to testosterone as men get older. Researchers measured testosterone and sex hormone-binding globulin (SHBG) in 890 men and found something that every man should understand: total testosterone drops by roughly 0.124 nmol/L per year, independent of illness or lifestyle factors. Free testosterone, the bioavailable form that actually drives physiological effects, declines even faster.

The numbers paint a stark picture. Using standard clinical thresholds, about 20% of men over 60 have hypogonadal testosterone levels. By 70, that figure climbs to 30%. By 80, it reaches 50%. This is not a disease that strikes a small subset of men. It is a near-universal biological process that accelerates with each passing decade.

What makes this study particularly valuable is its longitudinal design. Rather than comparing different men at different ages, the researchers tracked the same individuals over time. The within-subject decline was even steeper than cross-sectional estimates had suggested, meaning earlier studies likely underestimated the rate of testosterone loss. The Massachusetts Male Aging Study corroborated these findings, showing total testosterone declining at 1.6% per year and bioavailable testosterone at 2-3% per year when measured longitudinally.

Yet despite these findings being over two decades old, most men have no idea where their testosterone levels stand or whether they are declining faster than expected.

The Tracking Connection

This is exactly the kind of slow, invisible change that Kairos™ is designed to catch. A single testosterone test tells you almost nothing about trajectory. What matters is whether your rate of decline matches the expected curve or exceeds it, and whether interventions like sleep optimization, resistance training, or clinical treatment are actually bending that curve. Kairos turns isolated lab results into longitudinal intelligence, giving you and your provider the context to act before symptoms compound into clinical problems.

Ready to start tracking?

Kairos™ tracks, scores, and interprets the symptoms of midlife hormonal change — for both women and men.

Get Started

More from the newsroom

Back to all articles